Here are some of the consumer awareness initiatives developed by Wyeth to promote patient awareness of LYBREL^®.

LYBREL.com
Information about LYBREL for patients and consumers, including benefits of LYBREL, how it works, tips for taking LYBREL, a discussion guide, progress tracker, and more.

Important Safety Information

• Oral contraceptives (OCs) do not protect against HIV infection or other sexually transmitted diseases.
• When prescribing LYBREL, the convenience of having no scheduled menstrual bleeding should be weighed against the inconvenience of unscheduled breakthrough bleeding and spotting.
• OCs are contraindicated in women who have blood clots; breast, uterine, or liver cancers; a history of heart attack, stroke, or breast cancer; as well as those who are or may be pregnant.

• Serious risks associated with OCs include blood clots, heart attack, and stroke.
• LYBREL provides women with more hormonal exposure on a yearly basis (13 additional weeks of hormone intake per year) than conventional cyclic oral contraceptives containing the same strength of synthetic estrogens and similar strength of progestins.
• Scheduled withdrawal bleeding does not occur with the use of LYBREL, therefore, the absence of withdrawal bleeding cannot be used as a sign of an unexpected pregnancy and as such, unexpected pregnancy may be difficult to recognize. Although pregnancy is unlikely if LYBREL is taken as directed, if for any reason, pregnancy is suspected in a woman using LYBREL, a pregnancy test should be performed.
• The most commonly reported treatment emergent adverse events reported with LYBREL in a clinical trial were headache, dysmenorrhea, upper respiratory infection, vaginal bleeding (defined as metrorrhagia and vaginal hemorrhage), and nausea.

LYBREL and LYBREL with icon are registered trademarks of Wyeth.