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Selecting Patients

LYBREL® is a combination oral contraceptive that provides women with another birth control option. However, the concept of menses inhibition may not be for every woman.

LYBREL may be right for your patients if they agree with any of the following:

  • They are looking for a reliable form of birth control1,9
  • The idea of achieving amenorrhea is appealing to them
  • They are currently not trying to get pregnant
  • They are considering changing their birth control method
  • They find it easy to take medication on a daily basis
  • They are willing to accept the possibility of unscheduled or unplanned bleeding or spotting, especially when they start to use LYBREL1

LYBREL may NOT be right for your patients if any of the following describe them:

  • They are currently trying to get pregnant or are currently breastfeeding1
  • They smoke cigarettes (cigarette smoking increases the risk of serious cardiovascular side effects,1 especially if a patient is over 35)
  • They have blood clots, certain cancers, or a history of heart attack or stroke (see complete Prescribing Information for details)1
  • They find it difficult to take medication on a daily basis
  • They desire a monthly period
  • They find unscheduled or unplanned bleeding or spotting inconvenient1 and unacceptable

You can download and print this series of self-assessment statements and give copies to patient candidates for LYBREL in your office.

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Important Safety Information

  • Oral contraceptives (OCs) do not protect against HIV infection or other sexually transmitted diseases.
  • When prescribing LYBREL, the convenience of having no scheduled menstrual bleeding should be weighed against the inconvenience of unscheduled breakthrough bleeding and spotting.
  • OCs are contraindicated in women who have blood clots; breast, uterine, or liver cancers; a history of heart attack, stroke, or breast cancer; as well as those who are or may be pregnant.
The risks of serious cardiovascular side effects are substantially increased in women who smoke and use OCs, especially in women over age 35. Women who use oral contraceptives should be strongly advised not to smoke.
  • Serious risks associated with OCs include blood clots, heart attack, and stroke.
  • LYBREL provides women with more hormonal exposure on a yearly basis (13 additional weeks of hormone intake per year) than conventional cyclic oral contraceptives containing the same strength of synthetic estrogens and similar strength of progestins.
  • Scheduled withdrawal bleeding does not occur with the use of LYBREL, therefore, the absence of withdrawal bleeding cannot be used as a sign of an unexpected pregnancy and as such, unexpected pregnancy may be difficult to recognize. Although pregnancy is unlikely if LYBREL is taken as directed, if for any reason, pregnancy is suspected in a woman using LYBREL, a pregnancy test should be performed.
  • The most commonly reported treatment emergent adverse events reported with LYBREL in a clinical trial were headache, dysmenorrhea, upper respiratory infection, vaginal bleeding (defined as metrorrhagia and vaginal hemorrhage), and nausea.

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